TY - JOUR AU - Isaev, S.G. AU - Blyzniuk, O.A. AU - Pavley, O.O. AU - Alekseeva, L.M. AU - Sheveleva, N.E. PY - 2020/03/11 Y2 - 2024/03/28 TI - Synthesis, structure and biological activity of aryl- and alcylamydes of 6-nitro-2-chlorbenzoic acid JF - Farmatsevtychnyi zhurnal JA - Farm Zh VL - 0 IS - 2 SE - Original Articles DO - UR - https://pharmj.org.ua/index.php/journal/article/view/842 SP - 40-44 AB - Preparative methods in one stage of receiving aleyl- and arylamides of 6-nitro-2-chlorbenzoic has been carried out. The composition of synthesized compounds was proved by the data of element, IR-, UV-, NMR-spectra and counter synthesis and the purity was controlled by the method of thin- layer chromatography.It was established, that amides of 6-nitro-2-chlorbenzoic acid belong to low toxic compounds acĀ­cording to classification by K.K. Sydorov and have bile-expelling, membraneprotective, antioxidanty, diuretic, fungistatic activity. These investigations helped to determine some behavior among conformation and biological activity of these biologically compounds. ER -