TY - JOUR AU - Zhuk, E. AU - Baranova, І. PY - 2019/02/12 Y2 - 2024/03/28 TI - Development of modern antimicrobial foam cleaning product technology JF - Farmatsevtychnyi zhurnal JA - Farm Zh VL - 0 IS - 1 SE - Pharmaceutical technology DO - UR - https://pharmj.org.ua/index.php/journal/article/view/316 SP - 49-55 AB - Baby's skin is more sensitive and dry, prone to atopy and needs special care, particularly attention should be paid to foam cleaning tools (shampoos, soaps, gels, etc.). Developing mild foam cleaning product for children medical and biological requirements for it must be taken into account. Modern tools for children's skin treatment should facilitate the resumption of lipid balance, provide moderate cleaning action, be hypoallergenic and not irritate the skin.The aim of the study was to develop a new efficient technologies of foam cleaning product with complex biologically active substances based on modern excipients. In developing baby foam cleaning product pharmacological and technological methods have been used.With the help of technological research was proved efficient technology of a new modern children detergent.The efficient technology of this detergent was perfected and includes seven stages, that are: weighing components, preparing a solution of surfactants («Euraanat LS3», «Lamesoft PO65», «Neopal LIS 80», kokamіdopropilbetain) dispersion of hydroxypropylmethylcellulose (HPC) glycerol, mixing a suspension in a solution of HPC surfactants, injection of the active substances (D-panthenol, allantoin, «JM Acti Care»), perfumes, humectants (glycerin, hydroxyethyl urea), the correction values of pH (lactic acid) and the injection of a preservative («Roconsal ND»), viscosity adjustment (sodium chloride).For each stage was determined the necessary temperature, speed and time of mixing. The flowchart of child detergent was developed. This technology has been tested and implemented in the production of «Scientific Research Centre of Pharmacy “Alliance of Beauty”» (Kyiv) on line N 1 for the production of cosmetic products «Intermash», Ukraine. ER -