@article{Klenina_Tsepelevski_Bannyi_Isaev_2019, title={The studying of the correlation between diuretic, haemostatic, deprimic, analgetic and anti-inflammatory activities and toxicity of ε-carboxypentyl-amides R-benzenesulfonyloxamine acids derivatives and their molecules structure quantum-chemical parameters}, url={https://pharmj.org.ua/index.php/journal/article/view/710}, abstractNote={<p>The studying of the correlations between diuretic, haemostatic, deprimic, analgetic and ani-inflammatory activities and toxicity of 21 compounds s-carboxypentylamides R-benzenesulfonyloxamine acids derivatives and their molecules structure quantum-chemical parameters was carried out.</p> <p>The regression equations obtained by means of statistical analysis allow to conclude that the geometry structure and electronic density distribution in the researched compounds molecules influence significantly on all kinds of their biological activity and toxicity. The influence of the boundary orbitals energies, molecules polarity and lypophylic properties of the compounds on their biological activity and toxicity is also observed.</p&gt;}, number={1}, journal={Farmatsevtychnyi zhurnal}, author={Klenina, O.V. and Tsepelevski, A.O. and Bannyi, I.P. and Isaev, S.G.}, year={2019}, month={Sep.}, pages={54-63} }