Research of mushrooms lectins of RUSSULACEAE family. A genus Russula

  • L.V. Panchak -
  • L.V. Benzel -
Keywords: lectins, screening, Russula, agglutination, carbohydrate specificity, influence of the factors

Abstract

A result of screening lectins 14 species fruiting bodies of mushrooms genus Russula were represent. The lectins were found in 6 species (R cyanoxanta, R. foetens, R. nigricans, R. grisea, R. atropurpurea, R. aeruginea). Were investigated carbohydrate specificity found lectins. All lectins do not interacted with monosaccharides, but it is good inhibited group-specific substances of human bloods, bovine thyroglobulin and human immunoglobulin G. The lectins of mushrooms species Russula is inhere high lability. Hemagglu­tination activity strongly reduces after drying, freezing, precipitation of ammonium sulphate and ethanol, dialysis against water and buffer solutions. The possible mechanism of lectin lability is discussed.

References

Antonyuk VA Lectins and their raw materials. - Lviv: Kvart, 2005. - 554 p.

Ban M., Yoon H.J., Demirkan E. et al. // J. Mol. Biol. - 2005. - Vol. 351, No. 4. - P. 695—706.

Batterbury M, Tebbs C.A, Rhodes J.M. et al. // Exp Eye Res. - 2002. - Vol, 74, No. 3. - P. 361—370.

Fumio Yagi, Tomo Sakai, Noriko Shiraishi et al. // Mycoscience. - 2000. - Vol. 41. ó P. 323ó330.

Furukawa K., Ying R., Nakajima T. et al. // Exp. Clin. Immunogenet. - 1995 - Vol. 12 No. 4. P. 223-231.

Kent D, Sheridan C.M, Tomkinson H.A. et al. / / Wound Repair Regen. - 2003. - Vol. 11 No. 4. P. 285-291.

Kobayashi, Y., Kobayashi, K., and Umehara, K. et ai, J. Biol. Chem. - 2004. - Vol. 279, No. 51. P. 53048-53055.

Liu Q., Wang H. Ng T.B. // Biochim. Biophys. Acta. - 2006. - Vol. 1760, No. 12. - P. 1914—1919.

Parslew R., Jones K.T., Rhodes J.M. et al. / / British J. of Dermatology. - 1999. - Vol. 140, N 1. ó P. 56ó60.

Pemberton R.T. Agglutinins (lectins) from some British higher fungi. - Micol Res. - 1994 - Vol. 98 - P.277-290.

Roth W. F., Schöll I., Untersmayr E. et al. // Vaccine. - 2005. - Vol. 23, No. 21. P. 2703-2710.

Ueda H., Matsumoto H., Takahashi N. et al. // J. Biol Chem. - 2002. - Vol. 277, N 28. ó P. 24916-24925.

Zuber C., Paulson J.C., Toma V. et al. // Histochem Cell Biol. - 2003. - Vol. 120 No. 2. P. 143-160.

Published
2009-06-25
How to Cite
Panchak, L., & Benzel, L. (2009). Research of mushrooms lectins of RUSSULACEAE family. A genus Russula . Farmatsevtychnyi Zhurnal, (3), 115-122. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/994
Section
Original Articles