Synthesis and antioxidation activity of 2-methyl-7-aryl-[l,3]thlazolo[4,5- d]pyridazin-4(5H)-ones
Abstract
There were new 2-methyl-7-aryl-[l,3]thiazolo[4,5-d]pyridazin-4(5H)-ones synthsised. It was studied their antioxidation activity. It was found that compounds 5b and 5e show antioxidation activity. And the compound 5f is a typical prooxidant.
References
Gadilia OP, Andriychuk TR, Merkulov SP and others. // Ukrainian. biochem. . - 2002. - № 1, 74. -
Pp. 97-100.
Guben - Weil. // Methods of Organic Chemistry. - 2nd ed., P. - T. 2. Methods of analysis. - M .: Chemistry, 1967. - 1032 p.
Zateyshchikov AA, Zateyshchikov DA // Cardiology. 1998. № 20, pp. 426-432.
Ivanova OV, Sobolev GN, Karpov Yu.A. // Ter. archive. - 1997. - T. 69. - P. 75-78.
SI Kovalenko, IF Belenichev, OV Karpenko, and others. // Medication. - 2003. - № 1-2. - P. 68 - 72.
Lakin GV Biometrics. - M .: Higher. School, 1990. - 351 p.
Leonova MV, Levichev FA, Palatova L.Yu. etc. // Cardiology. 2000. № 5. P. 24-28.
Methods of evaluation of antioxidant activity of substances at the initiation of free radical processes in in vitro experiments: Method, recommendations. - К .: DFC MoH of Ukraine, 2002. - 26 p.
Olbinskaya LI, Sizova JM, Ushakova AV // Cardiology. - 2001. - № 41. - P. 29—32.
Pshenicin AI, Chigineva VV, Zolozova EA etc. // Ibid. - 2001. - №41. - P. 36-40.
Adam McCluskey et al. / / Australian journal of chemistry. - 2000, - 53 (11 & 12). P. 905-908.
Cadrillo C, Kilcoyne CM, Quyyumi A. et al. // Circulation. - 1998. - 97. - P. 851 -856.
Hartman J. // Ann Thorac Surg. - 1995 - 60. P. 789-792.
Makki, Mohamad S. I.; Faidallah, Hassan M. // J. of Chinese Chemical Society (Taipei). - 1996 - 43; 5. P. 433-438.
This work is licensed under a Creative Commons Attribution 4.0 International License.