Studying influence of some technological methods to the destruction processes in the infusion solution with malate
Studying of stabilizer sodium metabisulphite influence on glucose destruction processes in the infusion solution with malate-ions has been conducted.
Sodium metabisulphite decreases content of the 5-HMF and its precursors deoxglucosones in the investigated solution, as well as it inhibits glucose oxidation with hydrocarbonaceous chain release. The best quality indexes have been obtained in solutions with stabilizer and initial pH 5.13—6.0 sterilized at 110 °C during 30 minutes.
Gudz NI, Koritniuk RS, Musianovich VM etc. // Pharmacist. . - 2002. - № 3. - P. 79-82.
Gudz NI, Koritnyuk RS, Musianovich VM etc. // Ibid. - 2001. - № 2. - P. 80-84.
RS Koritniuk, IV Heintz, VV Trokhimchuk. etc. // Ibid. - 1999. - № 3. - P. 33 - 38.
Sinev DN, Gurevich I.Ya. Drug Technology and Analysis: A Guide for Pharmacists. - L .: Medicine, 1989. - 368 p.
Tereshkina OI, Isaeva IV // Pharmacy. - 1991. - T. 40, No. 6. - P. 24 - 28.
Titova AV :, Tereshkina OI, Isaeva IV // Ibid. 1988. T. 34, 4. 4. 84–88.
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