The development of capsule’s technology «Apinin”
Keywords:
androgenic preparations, phenolic hydrophobic preparation of propolis, arginine, capsules, technological properties
Abstract
The usage of new modern anti-friction matters and modification of mixture’s composition for capsulation allowed promoting the indexes of mixture’s friableness and conducting the process of capsulation on the industrial equipment. The capsules were got by the methods of moist granulation and direct mixing on the basis of arginine and FHPP. On the basis of the results of conducted researches optimum technology of capsules «Apinin» was chosen: it is a method of the direct mixing.
References
1. State Pharmacopoeia of Ukraine. - Type 1. - X .: RIREG, 2001. - 556 p.
2. Zakutsky AN, Subbotina TF // Questions of biological medical and pharmaceutical chemistry. - 2005. - № 1. - P. 7-12.
3. Laurent OB // International Endocrinological Journal. - 2007. - № 6 (12). - P. 102-106.
4. Mashkovsky M.D. // Medicines: In 2 volumes - 13th ed. - H.: Torsing, 1998. - 540 p.
5. Tikhonov OI, Romasy KP, Bondarenko OV // Bulletin of Pharmacy. - 2009. - № 4 (60). - P. 28-32.
6. Tikhonov OI, Sidorenko OV, Dankevich OS //Ibid. - 2004. - № 3 (39). - P. 28-31.
7. Tikhonov OI, Yarnykh TG, Chernykh VP, Zupanets IA, Tikhonova SO Theory and Practice of Propolis Drug Production / Ed. Acad. OI Tikhonov. - X .: Basis, 1998. - 384 p.
8. Chadaev VE, Kozub NI, Mironenko MV // International honey. magazine. - 2007. - № 4. - P. 79-82.
9. Handbook of Pharmaceutical Excipients. 6th ed. / Ed. by Ainley Wade and Paul J Weller. American Pharmaceutical Association. - Washington: The Pharmaceutical Press, London, 2006. - 651 p.
10. Gelatin Capsules Manufacturing. Capsule Technology International Ltd. - Canada, Montreal, 1992. - 17 p.
11. PharmazeutischeTechnologie fur Studium und Beruf / Rudolf Voigt. Unter Mitarb. Von Manfred Born-schein. - 8. Aufl. - Berlin: Wiesbaden: Ullstein Mosby, 1995. - 794 s.
12. Prospects of creating soft drugs on the basis of phenolic hydrophobic propolis drug / Yamykh T.G., Lukienko O.V., Khoklenkova N.V., Kozyr G.R. // XL Naykowa Conference pszczelarska. - Pulawy. - 2003. P. 138.
2. Zakutsky AN, Subbotina TF // Questions of biological medical and pharmaceutical chemistry. - 2005. - № 1. - P. 7-12.
3. Laurent OB // International Endocrinological Journal. - 2007. - № 6 (12). - P. 102-106.
4. Mashkovsky M.D. // Medicines: In 2 volumes - 13th ed. - H.: Torsing, 1998. - 540 p.
5. Tikhonov OI, Romasy KP, Bondarenko OV // Bulletin of Pharmacy. - 2009. - № 4 (60). - P. 28-32.
6. Tikhonov OI, Sidorenko OV, Dankevich OS //Ibid. - 2004. - № 3 (39). - P. 28-31.
7. Tikhonov OI, Yarnykh TG, Chernykh VP, Zupanets IA, Tikhonova SO Theory and Practice of Propolis Drug Production / Ed. Acad. OI Tikhonov. - X .: Basis, 1998. - 384 p.
8. Chadaev VE, Kozub NI, Mironenko MV // International honey. magazine. - 2007. - № 4. - P. 79-82.
9. Handbook of Pharmaceutical Excipients. 6th ed. / Ed. by Ainley Wade and Paul J Weller. American Pharmaceutical Association. - Washington: The Pharmaceutical Press, London, 2006. - 651 p.
10. Gelatin Capsules Manufacturing. Capsule Technology International Ltd. - Canada, Montreal, 1992. - 17 p.
11. PharmazeutischeTechnologie fur Studium und Beruf / Rudolf Voigt. Unter Mitarb. Von Manfred Born-schein. - 8. Aufl. - Berlin: Wiesbaden: Ullstein Mosby, 1995. - 794 s.
12. Prospects of creating soft drugs on the basis of phenolic hydrophobic propolis drug / Yamykh T.G., Lukienko O.V., Khoklenkova N.V., Kozyr G.R. // XL Naykowa Conference pszczelarska. - Pulawy. - 2003. P. 138.
Published
2020-07-09
How to Cite
Tikhonov, A., & Romas’К. (2020). The development of capsule’s technology «Apinin”. Farmatsevtychnyi Zhurnal, (5), 87-93. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/920
Section
Original Articles
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