Comparative pharmakokinetics of new potential cerebroprotektor VITIN-1 on the stage of absorption in norm and at cerebral ischemia

  • E.V. Krilova -
Keywords: pharmacokinetics, coordination compound of germanium, VITIN-1, ischemic stroke

Abstract

In the present work results of the pharmakokinetic researches of complex compound of germanium with oxyetilidendiphosphonic acid and pyracetamum (VITIN-1) in control and experimental rats. It is experimentally established that in conditions of ischemic stroke of cerebrum there is substantial modifica­tion of germaniumorganic compound’s pharmakokinetics parameters toward the acceleration of absorption process in a central blood flow, what the followings parameters testify to: constant of speed of absorption and period of semiabsorption.

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Published
2020-03-11
How to Cite
Krilova, E. (2020). Comparative pharmakokinetics of new potential cerebroprotektor VITIN-1 on the stage of absorption in norm and at cerebral ischemia. Farmatsevtychnyi Zhurnal, (2), 73-77. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/850
Section
Original Articles