Quantitative analysis of sodium oxacilline salt

  • М.Ye. Blazheevskiy -
  • S.Р. Karpova -
Keywords: spectrophotometry, oxacilline, peroxomonosulfate acid

Abstract

The kinetic of couplied reactions of S-oxidation and perhydrolysis of oxacilline with potassium peroxomonosulfate in alkaline medium is studied by light absorbance increase of a forming product at 282 nm. The procedure of the quantitative analysis of sodium oxacilline salt in powder by spectrophotometric-kinetic method is elaborated with using triple potassium Caro salt solution («Охопе») as a reagent. RSD = 1,90 %. The results of analysis by the method developed and standard pharmacopoeic techniques have been conformed well (δ = - 0,23 %).

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Published
2019-10-29
How to Cite
BlazheevskiyМ., & Karpova, S. (2019). Quantitative analysis of sodium oxacilline salt. Farmatsevtychnyi Zhurnal, (3), 64-69. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/802
Section
Original Articles