Synthesis and antimicrobial activity of geterilsubstituted phosphonium salts

  • A.V. Gumenna -
  • О.М. Bukachuk -
  • S.Ye. Deineka -
  • P.I. Yagodinets -
  • O.V. Skripskaya -
Keywords: antimicrobial activity, phosphonium salts, synthes, heterocycles

Abstract

The synthesis of new phosphonium salts, containing piperidinic, pirrolidinic, indolic, benzofuranic, isoxazolic, benzimidazolic, quinolinic, coumarinic heterocycles is carried out. The structure of prepared products was confirmed by analytical and spectral data.

The authors have investigated the antimicrobial activity of prepared products pertaining to 6 test cultures of microorganism.

References

1. Georgievsky VP, Komissarenko NF, Dmitruk SE Biologically active substances of medicinal plants. - Novosibirsk: Science, 1990. - 333 p.
2. Kozminykh VA, Shavkunova GA, Berezina ES and others. // Chemical formats. . - 1994. - T. 28, No. 2. - P. 31-35.
3. Lysova EA // Journal. microbiol. - 2000. - № 2. - P. 63-66.
4. Malishevskaya AV, Bukachuk AN, Dayneka SE // Beech. Honey. Herald. -2003. - Vol. 7, No. 3. - P. 123—127.
5. Mashkovsky M.D. Medicines. - M .: New Wave, 2005. - 1206 p.
6. Moroz VM, Paliy GK, Voliansky Yu.L. // Vis. Vinnytsia. over. honey. un-tu. - 2000. - Vol. 4, No. 2. - P. 260-264.
7. Prokopchuk ZM Comparative study of antimicrobial and biological properties of suppositories: Abstract ... Cand. honey. Sciences: 03.00.07. - Vinnitsa, 2001.
8. Herbal remedies / Ed. NP Maksyutina. - K .: Health, 1985. - 280 p.
9. GV Romanov, OK Pozdeev, GK Gilmanova etc. // Chemical Pharmac. . - 1990. - № 6. - P. 28-30.
10. OA Skripskaya, PI Yagodinets, and IN Chernyuk. etc. // Zh. total chemistry. - 1992. - T. 62, no. 3. P. 661-667.
11. Turkevich M., Vladimirskaya O., Lesik R. Pharmaceutical chemistry. - Vinnitsa: The New Book, 2003. - 464 p.
12. VV Shelest. Investigation of some quinoline compounds and fatty-aromatic ketones in the Ortolev-King reaction. Ph.D. Chernivtsi. 1975. - 142 p.
13. PI Yagodinets, OV Skripskaya, NG Prodanchuk et al. // Chemical Pharm. . - 1992. - T. 26, No. 5. - P. 59-61.
14. PI Yagodinets, OV Skripskaya, IN Chernyuk. in dp. // Journal. total chemistry. - 1991. - T. 61, no. 8, pp. 1856-1862.
15. PI Yagodshets, IN Chernyuk, and EM Volynskaya. etc. // Ibid. - 1984. - T. 54, no. 4. P. 772-775.
16. Rао В.Р. and Rao T.V.P. / / Indian J. Chem. - 1986. - Vol. 25, No. 4. P. 413-415.
Published
2019-10-29
How to Cite
Gumenna, A., BukachukО., Deineka, S., Yagodinets, P., & Skripskaya, O. (2019). Synthesis and antimicrobial activity of geterilsubstituted phosphonium salts. Farmatsevtychnyi Zhurnal, (3), 49-56. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/799
Section
Original Articles

Most read articles by the same author(s)