Synthesis and antiviral activity of 2-methyl-7-thienyl-[l,3]thiazolo[4,5-d]pyridazin-4(5H)-ones

  • S.A. Demchenko -
  • M.O. Lozinskii -
Keywords: [l,3]thiazolo[4,5-d]piridazine-4(5H)-ones; antiviral activity, H1N1, H3N2; H5N1; Flu B, SARS; selectivity index

Abstract

There were new 2-methyl-7-thienyl-[l,3]thiazolo[4,5-d]pyridazin-4(5II)-ones synthsised. It was studied their antiviral activity against viruses H1N1, H3N2, H5N1, Flu B and SARS. It was found that compounds 6c and 6d show high antiviral activity against H1NI and are recommended for further investigations.

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Published
2019-10-29
How to Cite
Demchenko, S., & Lozinskii, M. (2019). Synthesis and antiviral activity of 2-methyl-7-thienyl-[l,3]thiazolo[4,5-d]pyridazin-4(5H)-ones. Farmatsevtychnyi Zhurnal, (6), 20-25. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/741
Section
Original Articles