Pyrogen test of polyelektrolitical infusion solution «Glutacin»

  • М. V. Zdrajkovskaja -
  • T. V. Torkhova -
Keywords: infusion solution, sterilization, pyrogens, test-dose, initial temperature, maximal increase of temperature

Abstract

There are the results of pyrogen test researches of polyelectrolytical infusion solution «Glutacin» are resulted in the article. It is found that solutions, which were sterilized at 120 °C — 12 min. and at 105 °C — 45 min., are remained pyrogen-free after preparing and in the process of storage a term 24 months.

References

1. State Pharmacopoeia of Ukraine / State Enterprise "Scientific Expert Pharmacopoeial Center". - Type 1. - Kharkiv: RIREG, 2001. - 556s.
2. Zhidkov YB, Kolotilov LV Infusion-transfusion therapy for infectious diseases in children and adults. - M .: Medpressinform, 2005. - 302s.
3. Torkhova T.V. Development of technologies of polyionic solutions with energy substrates for infusions: Ph.D. - K., 1989. - 156 p.
4. Pertsev IM, Piminov OH, Sloboyanyuk MM etc. Pharmaceutical and medical-biological aspects of medicines. - In: New Book, 2007. - 728 p.
5. EL Khaleev, SA Tikhonova, and LA Pechenezhskaya. // Doctor. - 2002. - № 10.
6. British Pharmacopoeia - London. - 2009.
7. European Pharmacopoeia. 3rd Edition. Council of Europe. Strasbourg. - 1997. - 1799p.
8. The United States Pharmacopoeia 30 - National Formulary 25 / The United States Pliarmacopeial Convention. - 2007
Published
2019-10-29
How to Cite
ZdrajkovskajaМ. V., & Torkhova, T. V. (2019). Pyrogen test of polyelektrolitical infusion solution «Glutacin». Farmatsevtychnyi Zhurnal, (5), 66-69. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/731
Section
Original Articles