Development of methods for nimesulide isolation from biological objects

  • I.O. Iurchenko -
  • V.P. Buryak -
  • O.V. Korotina -
Keywords: identification, isolation, quantitation, nimesulide, chemical and toxicological analysis

Abstract

A comparative evaluation of methods non-steroidal anti-inflammatory agent nimesulide isolation from biological objects has been done. It was found that the most effective isolating method is with acetonitrile. Identification (TLC) and quantification (UV-spectrophotometric) was carried out after preliminary purification of extracts by TLC and the extraction method. The results can be used for chemical and toxicological analysis of nimesulide post-mortem poisonings.

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Published
2019-07-01
How to Cite
Iurchenko, I., Buryak, V., & Korotina, O. (2019). Development of methods for nimesulide isolation from biological objects. Farmatsevtychnyi Zhurnal, (2), 95-98. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/686
Section
Original Articles