Spectrophotometric determination of terbinafine in tablets based on the reaction with bromocresole green

  • J.V. Burlaka -
  • O.O. Tarkhanova -
  • A.S. Korzhova -
  • S.O. Vasjuk -
  • I.M. Keytlin -
Keywords: spectrophotometry terbinafine, sulphonphthalein dyes. bromocresole green, quantitative determination

Abstract

A new precise and sensitive spectrophotometric method for the quantitative determination of terbinafine in tablets based on the reaction with bromocresole green is proposed. Validation characteristics such as linearity, application range, precision, accuracy and robustness are also determined. The method is valid according to these characteristics.

References

1. Mashkovsky M.D. Medicines: In 2 tons / M.D. Mashkovsky. - M .: New wave, 2002. - T 2. - S. 358-359.
2. Abdel-Moety E.M., Kelani K.O., Abou al-Alamein A.M. // Boll. Chim. Farm. - 2002. - Vol. 141, No. 4. - R. 267-273.
3. Dotsikas Y., Apostolou C., Kousoulos C. [et al.] // Biomed. Chromatogr. - 2007. - Vol. 21, No.
2. - R. 201-208.
4. Cardoso S.G., leggli C.V., Pomblum S.C. // Pham. - 2007. - Vol. 62, No. 1. - P. 34-37.
5. Cardoso S.G., Schapoval E.E. // J. AOAC Int. - 1999. - Vol. 82, No. 4. - R. 830-833.
6. El-Saharty Y.S., Hassan N.Y., Metwally F.H. // J. Pharm. Biomed. Anal. - 2002. - Vol. 15, No. 28. - R. 569-580.
7. Erk N. // Pham. - 2007. - Vol. 59, No. 3. - P. 183-186.
8. Florea M., Monciu C.-M. // Farmacia. - 2008. - Vol. 36, No. 4. - R. 393-401.
9. Brignol N., Bakhtiar R., Dou L. [et al.] // Rapid Commun Mass Spectrom. - 2000. - Vol. 14, No. 3. - R. 141-149.
10. Rahman N., Hejaz-Azmi S.N. // J. of Pharm. and Biom.l Anal. - 2000.- No. 24. - R. 33-41.
Published
2019-07-01
How to Cite
Burlaka, J., Tarkhanova, O., Korzhova, A., Vasjuk, S., & Keytlin, I. (2019). Spectrophotometric determination of terbinafine in tablets based on the reaction with bromocresole green. Farmatsevtychnyi Zhurnal, (2), 66-69. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/680
Section
Original Articles

Most read articles by the same author(s)