Experimental study of pharmacological activity of garden nasturtion on necrotic ulcers model in rats

  • S.M. Drogovoz -
  • S.M. Marchyshyn -
  • K.G. Shchokina -
  • H.R. Kozyr -
  • O.O. Baev -
Keywords: Tincture of garden nasturtium, necrotic ulcers model, antialterative action, reparative action

Abstract

Moderate antialterative action and evidence reparative action of garden nasturtium tincture on the necrotic ulcers model is determined. For antialterative activity tincture of garden nasturtium dominated referent medicines diclofenac sodium and quercetin.

References

1. Babak O.Ya. Application of nonsteroidal anti-inflammatory agents in therapy / O.Ya.Babak, I.I. Knyazkova, IA Nestertsova // Ukrainian Therapeutic Journal. - 2007. - No. 2. - P. 4-11.
2. Barsukova E. Efficiency and safety of modern NSAIDs / E. Barsukova // Drugstore. - 2004. - No. 46 (467). - P. 7
3. Viktor O.P. Prevention and pharmacotherapy of gastropathy associated with the use of nonsteroidal, anti-inflammatory drugs (methodical recommendations) / O.P.Viktorov, N.V.Harchenko, L.I.Omelchenko, V.B.Nikolaenko and others. - K. - 2005. - 30 p.
4. Pre-clinical research of drugs: method. rivers / Ed. corporation member AMS of Ukraine O.V.Stefanova. - K .: Avicenna, 2001. - P. 263-261.
5. Kutsin R.V. Immunocorrective and anti-inflammatory properties of biologically active substances of some plants of Siberia / R.V.Kutsin, O.G.Rybaltuk. - Tomsk: Cedar, 2004. - 214 p.
6. Lapach SN Statistical methods in medical-biological research using Excel / SN Lapach, AV Chubenko, P.N. Babich. - K.: Morion, 2000. - 320 p.
7. Moybenko AA Contemporary notions about the biological role of flavonoids / A.A.Miybenko
VB Pavlyuchenko, VV Datsenko // Achievements of Biology and Medicine. - 2003. - No. 1. - P. 72-79.
8. Natural antioxidant agents in the experiment and clinic / VA Tumanov, N.O.Gorchakova, E.M.Gorban, and others. // Phytotherapy. A magazine - 2002. - No. 3-4. - P. 3-11.
9. Wednesday P.I. Pharmacognosy Medicinal herbs and phytoplanktons / P.I. Sereda, N.P.Maksytina, L.L. Davtyan. - Vinnitsa: New Book, 2006. - P. 252-259.
10. Contemporary ideas about mechanisms of therapeutic and side effects of NSAIDs / V. Mamchur, E. Pidleletnaya, O. Makarenko, etc. // Bulletin of Pharmacology and Pharmacy. - 2005. - No. 4. - P. 3-17.
11. Sokolov S.Ya. Phytotherapy and phytopharmacology: Manual for doctors. S.Ya.Sokolov - M .: Honey. Inform agency, 2000. - 976 p.
12. Strachunsky L. S. Nonsteroidal antiinflammatory drugs / L. S. Strachunsky, SN N. Kozlov. - Smolensk, 2000. - 50 p.
13. Shkilnik Z.V. Biologically active substances of grasses of large nasturtium (Tropaeolum majus L.) / Z.V.Shkilnik, O.O.Bayev // Materials of the XV International Congress of Students and Young Scientists - Ternopil: Ukrmedkniga, 2011. - P. 379.
14. Strigol S.Yu. Pharmacological properties and safety problems of NSAIDs use - selective and specific inhibitors of cyclooxygenase-2 / S.Yu.Strigol // Provizor. - 2005. - №2. - P. 37-42.
15. Shchokina K.G. Experimental substantiation of rational choice of modern and promising preparations with anti-inflammatory action: author's abstract. dis .... farm sciences - Kharkiv, 2006. - 19 p.
16. Hawkey C.J. Non-steroidal anti-inflammatory drugs: general risk and management. Comlementary roles for COX 2 inhibitor and proton pump inhibitor / C.J.Hawkey, M.J.S. Langman // Gut. - 2003. - Vol. 52. - P.600-808.
Published
2019-03-18
How to Cite
Drogovoz, S., Marchyshyn, S., Shchokina, K., Kozyr, H., & Baev, O. (2019). Experimental study of pharmacological activity of garden nasturtion on necrotic ulcers model in rats. Farmatsevtychnyi Zhurnal, (5), 92-95. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/596
Section
Original Articles

Most read articles by the same author(s)