Analgesic activity of S-derivatives of 5-heteryl-4-(r-amino)-1,2,4-triazol-3-thiol
Keywords:
1,2,4-triazole, analgesic activity, physico-chemical properties
Abstract
Studied the analgesic activity of S-derivatives of 5-heteryl-4-(R-amino)-1,2,4-triazole-3-thiols. It is established that the investigated compounds exhibit analgesic activity, and some exceed the standard of comparison analgin. Establishing the link between chemical structure and biological activity of the compounds.
References
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3. Pruglo Ye.S., Bilai I.M., Kaplushenko A.G. and others. Experimental study of the hypocholesterinmic action of some substituted 1,2,4-triazole // Zaporozhye. honey. journ 2009 Vol. 11, No. 2 P. 103-106.
4. Mashkovsky M. D. Medicines. M .: Medicine, 2010. - 1216 p.
5. Parchenko V.V., Panasenko O.I., Knysh Ye.G. and others. Neurotropic Activity of S-derivatives of 5- (Furan-2-yl) -4-R-1,2,4-triazole-3-thione // Pharmac. a magazine 2009 Vip 3 (9). - P. 34-37.
6. Shcherbyna R. O., Parchenko VV, Pavlov SV and others. Neuroprotective activity of S-derivatives of 1,2,4-triazole // Zaporozhye. honey. journ 2011. T. 13, No. 1. - P. 94-97.
7. Parchenko V.V., Panasenko O.I., Knysh Y. G. and others. Anti-inflammatory activity of S-derivatives of 5- (furan-2-yl) -4-R-1,2,4-triazole-3-thione // Ibid. 2009. T. 11, No. 4. - P. 100 - 102.
Published
2019-02-12
How to Cite
Safonov, A. A., Pruglo, E. S., Panasenko, O. I., & Knysh, E. G. (2019). Analgesic activity of S-derivatives of 5-heteryl-4-(r-amino)-1,2,4-triazol-3-thiol. Farmatsevtychnyi Zhurnal, (2), 84-87. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/422
Section
Original Articles
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