Development of sostva, technology and methods of standardization of tablets of «Tiotarin»
Keywords:
tablets, thioctic acid, taurine, saccharine diabetes, diabetic complications
Abstract
The development of combined preparations on the basis of thioctic acid and taurine is a perspective direction in creation of medications for the prophylaxis and treatment of diabetes complications. By means of physicochemical, technological, microbiological and biological research the combined medicinal preparation in a tablet form «Tiotarin» for the prophylaxis and treatment of diabetes complications has been developed. The research related to the choice of indexes and methods of quality control of the developed tablets has also been done.
References
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2. American Diabetes Association: Standards of Medical Care in Diabetes 2008 // Diabetes Care. 2008 V. 31, N 1. P. 12-54.
3. Zimmet P., Alberty K., Shaw J. Global and societal implications of the diabetes epidemic // Nature. 2001 V. 414, N 7. P. 782-787.
4. Kovalenko S. M. Investigation of some properties of taurine and thioctic acid substances for the purpose of creating a combined preparation for the treatment of diabetic complications // Actual questions of honey. science and practice. 2012. No. 2 (9). - pp. 33-36.
5. State Pharmacopoeia of Ukraine / State. Scientific and Experimental Pharmacopoeia Center. 1 st view. - Kharkiv: RIERER, 2001. - 556 p.
6. State Pharmacopoeia of Ukraine. Dopov 2. / State Scientific and Experimental Pharmacopoeia Center. 1 st view. Kharkiv: RIERER, 2001. - 620 p.
7. State Pharmacopoeia of Ukraine. Dopov 3. / State Scientific and Experimental Pharmacopoeia Center. 1 st view. Kharkiv: RIERER, 2001. 280 p.
8. Kovalenko S. M. Choice of auxiliary substances in the creation of combined pills for the treatment of diabetic complications // Problems ecologist. honey. genetics clinic immune 2012. Vip. 1 (109). - P. 333-340.
9. Kovalenko S. M. Development of the technology of combined pills for the treatment of diabetic complications // Ibid. 2012. Vip. 3 (111). - pp. 288-295.
10. Kovalenko S. M. Investigation of the influence of auxiliary substances on the pharmaco-technological properties of combined pills for the treatment of diabetic complications // Prob. sciences works of NMAPE employees. P. L. Shupika. 2012. - Issue 21., Kn. 4. pp. 419-424.
11. Kovalenko S. M., Shtrigol S. Yu. Experimental study of anti-diabetic activity of tablets "Thiotarin" // Problems ecologist. honey. genetics clinic immune 2012. Vip. 4 (112). S. 296-301.
12. Kovalenko S. M., Shklyaev S. A., Kovalenko S. M. Validation of HPLC-method of determination of thioctic acid in a combined drug for the treatment of diabetic complications // Management, economics and quality assurance in pharmacy. 2012. No. 4 (24). - P. 19-24.
Published
2019-02-12
How to Cite
KovalenkoS. М. (2019). Development of sostva, technology and methods of standardization of tablets of «Tiotarin». Farmatsevtychnyi Zhurnal, (2), 60-65. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/418
Section
Pharmaceutical technology
This work is licensed under a Creative Commons Attribution 4.0 International License.
