The methods of synthesis, physico-chemical properties and further transformationsof 4-amino-1,2,4-triazole-3-thiones

  • M. O. Shcherbak Zaporizhzhia state medical university
  • A. G. Kaplaushenko Zaporizhzhia state medical university
Keywords: 1,2,4-triazol, transformations, physico-chemical properties

Abstract

The analysis of the literature on methods of synthesis and transformations were studied among 4-amino-1,2,4-triazol-3-thiones. The reactions of electrophilic addition and substitution, cyclocondensation and catalytic condensation are analyzed. Some regularity between the influence of substances’ structure and their physico-chemical properties were set. The study of pharmacological properties of these compounds is offered as rational direction of chemical industry in future.

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Published
2019-02-12
How to Cite
Shcherbak, M. O., & Kaplaushenko, A. G. (2019). The methods of synthesis, physico-chemical properties and further transformationsof 4-amino-1,2,4-triazole-3-thiones. Farmatsevtychnyi Zhurnal, (2), 10-19. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/412