Selective polarimetric determination of lactose monohydrate in two-component excipient «StarLac»

  • G. V. Anelchyk Аdditional liability company «InterHim», Odesa
  • I. I. Leonenko A. V. Bogatsky Physico-chemical Institute of Nаtional academy of Sciences of Ukraine, Odesa
  • Yu. V. Scrypynets A. V. Bogatsky Physico-chemical Institute of Nаtional academy of Sciences of Ukraine, Odesa
  • A. V. Yegorova A. V. Bogatsky Physico-chemical Institute of Nаtional academy of Sciences of Ukraine, Odesa
  • V. P. Antonovich A. V. Bogatsky Physico-chemical Institute of Nаtional academy of Sciences of Ukraine, Odesa
Keywords: excipient StarLac, lactose monohydrate, polarimetry

Abstract

A simple, express and selective polarimetric method for determination of lactose monohydrate in a two-component excipient StarLac (StarLac, Meggle, Germany) was proposed. Contents of lactose monohydrate, in a count on a dry substance, conforms to the requirements of analytical-regulatory documentation of producer.

References

1. State Pharmacopoeia of Ukraine / State Enterprise "Scientific Expert Pharmacopoeia Center". - 1st kind. Extra 2. - Kharkiv: State Enterprise "Scientific Expert Pharmacopoeia Center", 2008 - 620 p.
2. Finger A. Determination of Lactose in StarLac by HPLC. - 2012. - Doc.Nr. MEGPV-10107-E., Meggle.
3. Lactose / D-GalactoseUV-method for the determination of lactose and D-galactose in foodstuffs and other materials, BOEHRINGER MANNHEIM / R-BIOPHARM. – http://www.hottay.ru/Files/lactose_galactose_d_englisch_10176303035.pdf
Published
2019-02-12
How to Cite
Anelchyk, G. V., Leonenko, I. I., Scrypynets, Y. V., Yegorova, A. V., & Antonovich, V. P. (2019). Selective polarimetric determination of lactose monohydrate in two-component excipient «StarLac». Farmatsevtychnyi Zhurnal, (3), 73-77. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/406
Section
Original Articles