Choice of excipients to develop composition tablets with esomeprazole

  • S. M. Gureyeva Farmak Joint-Stock Company, Kyiv
Keywords: auxiliary substance, technology, tablets

Abstract

Researched the physic-chemical properties of the active ingredient esomeprazole. To improve technological performance tableting mass at different stages of the process (making granules for tableting mass, pressing tablets) are selected and introduced excipients. Studies of their functional purpose, investigated and confirmed compatibility support and active substances and intermediates studied technological characteristics from the point of view of their pharmacological characteristics of the technological requirements of the State Pharmacopoeia of Ukraine. For the development of technology and tablets esomeprazole-cores used wet granulation method. As a result of technological and biopharmaceutical studies selected quality of tablets esomeprazole-cores.

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Published
2019-02-12
How to Cite
Gureyeva, S. M. (2019). Choice of excipients to develop composition tablets with esomeprazole. Farmatsevtychnyi Zhurnal, (3), 62-66. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/404
Section
Pharmaceutical technology