Study osmotic properties vaginal suppositories combined exposure with anti-microbial and anti-inflammatory activity

  • Z. V. Maleckа P. L. Shupik National Academy of Post-graduate Education, Kyiv
  • L. L. Davtyan P. L. Shupik National Academy of Post-graduate Education, Kyiv
Keywords: polycystic ovary syndrome, osmotic activity, vaginal suppositories, suppository bases

Abstract

A study to determine the osmotic activity suppository bases (hydrophilic and hydrophobic) and selecting the most appropriate samples for further pharmaceutical development suppositories. Selected samples meet medical and biological requirements that apply to drugs with local action. It is set experimental researches, that osmotic activity of hydrophilic bases in two times exceeds activity of hydrophobic bases. On osmotic activity can hydrophobic bases be placed in a next sequence – 6>2>5>1, and hydrophilic – 3>10>8>9>4>7.

On the basis of experimental researches by us grounded choice of next hydrophobic model standards of suppository bases - 1, 5 and 6. The study of index of osmotic activity of model standards enables to make decision in relation to subsequent addition superficially active substances in the complement of the probed bases.

References

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Published
2019-02-12
How to Cite
MaleckаZ. V., & Davtyan, L. L. (2019). Study osmotic properties vaginal suppositories combined exposure with anti-microbial and anti-inflammatory activity. Farmatsevtychnyi Zhurnal, (3), 57-61. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/403
Section
Pharmaceutical technology