Evidence-based pharmacy: definition of the control regime for the medicines in the pharmaceutical correction schemes of the opioid dependence

  • V. V. Shapovalov Kharkiv Medical Academy of Post-graduate Education
  • I. V. Linskiy State Institution «Institute of Neurology, Psychiatry and Addiction of National Medical Academy of Science of Ukraine», Kharkov
Keywords: evidence-based pharmacy, control regime, drugs, pharmaceuticals correction, opioid addiction


Defined forensic and pharmaceutical accessibility criteria – control regime for drugs in the pharmaceutical correction schemes for opioid drug dependence through institutional, clinical and pharmacological studies. There are three schemes of the pharmaceutical correction of opioid dependence: a standard basic, standard basic plus an atypical antipsychotic clozapine, standard basic plus antipsychotic risperidone. It was proved that the addition of atypical antipsychotics to the standard basic pharmaceutical correction significantly increases the efficiency of the symptoms of opioid withdrawal (distemiya, anxiety, irritability, compulsive craving for drugs), and the inclusion of neuroleptic risperidone increases the relief of insomnia of the drug addicted patients.


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How to Cite
Shapovalov, V. V., & Linskiy, I. V. (2019). Evidence-based pharmacy: definition of the control regime for the medicines in the pharmaceutical correction schemes of the opioid dependence. Farmatsevtychnyi Zhurnal, (3), 35-40. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/399
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