The selections of optimal technology of maclura oil extract preparation

  • V. A. Korotkov National University of Pharmacy, Kharkiv
  • A. S. Kukhtenko National University of Pharmacy, Kharkiv
  • Y. V. Gladukh National University of Pharmacy, Kharkiv
Keywords: Maclura, oil extract, isoflavonoids, phytosterols, rotary-pulsation apparatus


The Osage orange fruits are rich with such lipophilic substances as isoflavones, phytosterols, triterpenes, phospholipids, tocopherols, and also they contain a wide range of polyunsaturated fatty acids. One of the most effective was to extract lipophilic substances from plant material is the oil extraction. Vegetable oils are affordable and non-toxic extractants to the human body.

The Osage orange fruits, grown in southern Kazakhstan, and their oil extractions were the objects of the study. There were used such methods as: maceration, extraction with alternative pressure, and rotary-pulsation apparatus extraction.

The optimal technology for the oil extraction from the Osage orange fruit is developed in this paper. The optimum extraction conditions are set. The qualitative and quantitative evaluation of the extracts is conducted.

On the basis of the research the method of using the rotary-pulsation apparatus extraction was recognized as the most effective. It is noted that the yield of BAS according to the method of extraction is 48% more than at the maceration and 30% more than at the extraction with alternative pressure. The advantages of this method over the other are also in a small time of extraction and high performance. The optimal conditions for this method are selected and the main stage technology of the extract was developed.


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How to Cite
Korotkov, V. A., Kukhtenko, A. S., & Gladukh, Y. V. (2019). The selections of optimal technology of maclura oil extract preparation. Farmatsevtychnyi Zhurnal, (6), 36-41. Retrieved from
Pharmaceutical technology