Development of modern antimicrobial foam cleaning product technology

  • E. Zhuk National University of Pharmacy, Kharkiv
  • І. Baranova National University of Pharmacy, Kharkiv
Keywords: surfactants, foam cleaning product, technology, industrial production

Abstract

Baby's skin is more sensitive and dry, prone to atopy and needs special care, particularly attention should be paid to foam cleaning tools (shampoos, soaps, gels, etc.). Developing mild foam cleaning product for children medical and biological requirements for it must be taken into account. Modern tools for children's skin treatment should facilitate the resumption of lipid balance, provide moderate cleaning action, be hypoallergenic and not irritate the skin.

The aim of the study was to develop a new efficient technologies of foam cleaning product with complex biologically active substances based on modern excipients. In developing baby foam cleaning product pharmacological and technological methods have been used.

With the help of technological research was proved efficient technology of a new modern children detergent.

The efficient technology of this detergent was perfected and includes seven stages, that are: weighing components, preparing a solution of surfactants («Euraanat LS3», «Lamesoft PO65», «Neopal LIS 80», kokamіdopropilbetain) dispersion of hydroxypropylmethylcellulose (HPC) glycerol, mixing a suspension in a solution of HPC surfactants, injection of the active substances (D-panthenol, allantoin, «JM Acti Care»), perfumes, humectants (glycerin, hydroxyethyl urea), the correction values of pH (lactic acid) and the injection of a preservative («Roconsal ND»), viscosity adjustment (sodium chloride).

For each stage was determined the necessary temperature, speed and time of mixing. The flowchart of child detergent was developed. This technology has been tested and implemented in the production of «Scientific Research Centre of Pharmacy “Alliance of Beauty”» (Kyiv) on line N 1 for the production of cosmetic products «Intermash», Ukraine.

References

1. Monakhov K. N., Ocelenko SA Application of Modern Moisturizers in the Disruption of Each Barrier // Klin. dermatology and venereology. - 2009. - No. 1. - P. 72-75.
2. Studenikin VM, Studenikina N.I. Skin care of children of the first years of life: neuropathyatric aspects // Treatment doctor. - 2008. - No. 3. - P. 2-7.
3. Surfactants and compositions, ed. Pletnev M. Yu. - 2004. - Moscow: Cosmetics and Medicine. - 780 s.
4. Tikhomirov V.K. Foams. Theory and practice of their acquisition and destruction. - 2nd ed., Pererab. - Moscow: Chemistry, 1983. - 264 p.
5. Shampoos for hair and bath products. Method for determining the content of chlorides: GOST 26878-96. - Introduction. Apr 24, 1986 - Moscow: Publishing House of Standards, 1986. - 3 p.
6. Gudz O. V. Modern requirements for consumer properties and safety of preservatives for cosmetic products // Visn. Vinnytsia National un-th - 2004. - Vol. 8, No. 2. - P. 409-413.
7. Perfumery and cosmetic products. Rules of acceptance, sampling, methods of organoleptic tests: DSTU 5009: 2008. - (In lieu GOST 29188.0-91). - Introduction. since 01.01.2009. - 7 s.
8. Cosmetic products. Method for determination of hydrogen pH: GOST 29188.2-91. - Introduction. 01.01.98. - Moscow: Publishing House of Standards, 1992. - 3 p.
9. Substances surfactant and detergents. Determination of the content of anionic substance by direct two-phase titration by hand or by mechanical means: GOST 28954-91. - Introduction. 01/01/92. - Moscow: Publishing House of Standards, 1991. - 3 p.
10. Makeup for skin and hair cleaning. General specifications: DSTU 4315: 2004 - For the first time. (Effective from 01.07.2005). - K .: Derzhspozhyvstandart of Ukraine, 2005. - 8 p.
11. Petroleum products. Methods for determining kinematic and calculation of dynamic viscosity: GOST 33-82. (In lieu GOST 33-82). - Introduction. May 01, 1994 - Moscow: Publishing Standards, 1994. -17 p.
12. Synthetic detergents. Method of determination of foaming ability: GOST 22567.1-77 (ST SEV 4155-83). (In lieu GOST 22567.1-77). - Introduction. May 01, 86 - M .: Publishing of Standards, 1986. - P. 1-6.
Published
2019-02-12
How to Cite
Zhuk, E., & BaranovaІ. (2019). Development of modern antimicrobial foam cleaning product technology. Farmatsevtychnyi Zhurnal, (1), 49-55. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/316
Section
Pharmaceutical technology