Development of the technology of cream for diabetic foot

  • A. Goncharova National University of Pharmacy, Kharkiv
  • I. Baranova National University of Pharmacy, Kharkiv
Keywords: diabetes, diabetic foot, emulsion, cream, technology, α-lipoic acid, urea, tea tree oil.

Abstract

Diabetes mellitus is one of the most difficult problems of our time. Aggravating factors in the course of the disease are numerous complications that lead to disability and early mortality. One of the most dangerous complications of diabetes mellitus considered to be diabetic foot syndrome. Existing tools for diabetes therapy available in the market of Ukraine does not provide an optimal impact on all parts of the pathogenesis of this syndrome. Products for preventing diabetic foot syndrome ulcer forms presented by foreign cosmetic products.

The aim of our work was to develop a rational technology of cream for use in diabetic foot with a stepwise description and considering temperature, mixing regime, the duration of each stage, etc.

Samples with α-lipoic acid,  urea and tea tree oil were selected as objects for cream technology research. Based on thermogravimetric analysis and structural-mechanical studies substantiated the optimum temperature for incorporating active components of developed cream. Also during technological research, we have developed technology of cream based on α-lipoic acid and urea for use in diabetic foot and composed technological scheme of production.

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Published
2019-02-12
How to Cite
Goncharova, A., & Baranova, I. (2019). Development of the technology of cream for diabetic foot. Farmatsevtychnyi Zhurnal, (3), 35-41. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/286
Section
Pharmaceutical technology