Clinical and economic analysis of pharmacotherapy for patients with ulcer in the terms of prepaid funds

  • A. A. Kotvitskaya National University of Pharmacy, Kharkiv
  • V. P. Khodakovskaya National University of Pharmacy, Kharkiv
Keywords: peptic ulcer, clinical and economic analysis, prepaid funds, pharmaceutical provision of patients


Digestive diseases are the third leading cause of appeals in all age groups for medical help after the pathologies of the circulatory and respiratory system. In Ukraine, the number of patients needing specialized gastroenterological care is annually increasing. In addition, medical and demographic situation is exacerbated under conditions of a difficult social and economic situation.

Previous experience of the pharmaceutical provision of prepaid funds’ (PF) members by medications pointed out the need to improve their cost-effectiveness.

In order to analyze pharmacotherapy of gastroenterological patients, a clinical and economic analysis of 4069 medical prescriptions of Zhytomyr region PF’ members with gastric ulcer and duodenal ulcer treated for the period 2010–2014 was conducted.

According to ABC-analysis in the analyzed period the proportion of medications included in group A, increased by 5.95%. The proportion of medications of group B practically unchanged and was 18,49%, 21,62%, 23,23%, 20,95% та 22,92% respectively. However, in 2014 the proportion of medications of group С decreased at 10.38% in comparison with 2010.

VEN-analysis showed that the highest number of medications (69.79%) belongs to the category N (not necessary), that defines the need for further search for ways to reduce the costs of not necessary medications. Medications of the category E (essential) accounted for 9.38% of the total assortment and category V (vital) represented by 20.83%.

As a result of integrated clinical and economic analysis, it was found that in 2014 the largest part of the costs 25 281.04 UAH (42,76%), associated with the pharmaceutical provision of patients with peptic ulcer disease, accounts for 8 INN, which were the most expensive (group A) and vital (Group V).


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How to Cite
Kotvitskaya, A. A., & Khodakovskaya, V. P. (2018). Clinical and economic analysis of pharmacotherapy for patients with ulcer in the terms of prepaid funds. Farmatsevtychnyi Zhurnal, (5), 23-29. Retrieved from
Management of pharmacy