Dynamics of prostate protectors assortment in the state formulary of medicines of 1-9 issues

  • І. V. Gadyak Ivano-Frankivsk National Medical University
  • B. P. Hromovyk Danylo Halytsky Lviv National Medical University
Keywords: prostatitis, State Formulary of Medicines, updating of assortment, State Register of Medicines of Ukraine, depth of assortment

Abstract

Prostatitis is one of the most frequent urology diseases of men of reproductive age. Recommendations for rational pharmacotherapy prostatitis are included into the State Formulary of Medicines, which is reviewed and updated annually. Thus, the aim of our work was to study the dynamics of the assortment of prostate protectors.The State Formulary of Medicines of 1–9 issues and the State Register of Medicines of Ukraine dated 01. 08. 2017 were the materials of the research. The methods of search, content analysis, statistics, comparison and generalization were applied.  It was established that the first, second and third issues of State Formulary of Medicines include three therapeutic and chemical subgroups of prostate protectors: alpha-adrenergic receptors antagonists (G04CA), testosterone-5-alpha reductase inhibitors (G04CB), other drugs used in benign prostatic hypertrophy (G04CX). And since the fourth issue – only the first two subgroups of prostate protectors were icnluded. Assortment prostate protectors was stabilized in State Formulary of Medicines of 8, 9 issues. Depth of assortment of the State Formulary of Medicines of the ninth issue is 55,8% in comparison with the State Register of Medicines of Ukraine along with 100% index for prostate protectors trade names based on alfuzosin, terazosin (G04CA – Аntagonists of alpha adrenergic receptors), finasteride and dutasteride (G04CB – Inhibitors of testosterone-5-alpha reductase), as well as the absence of drugs based on silodosin, dutasteride-tamsulosin, solifenacin-tamsulosin (G04CA – Antagonists of alpha-adrenergic receptors) and prostate protectors with G04CX – Other drugs used in benign prostatic hypertrophy.

References

1. Popovich V.P. Comparative analysis of the range of hepatoprotectors in the four issues of the State Form of Drugs // Military Medicine of Ukraine. - 2012. - Vol. 13, No. 2. - P. 84-87.
2. Gromovik B.P., Prokip S.Ye. Investigation of formular lists of drugs for palliative and hospice medicine // Pharmac. journ - 2013. - No. 4. - P. 27-34.
3. State Form of Medicines. Issue first. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2009 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
4. State drug form. Issue the second. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2010 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
5. State drug form. Release third - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2011 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
6. State Form of Medicines. The fourth issue. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2012 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
7. State Form of Medicines. Issue fifth. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2013 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
8. State Form of Medicines. The sixth issue. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2014 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
9. State Form of Medicines. Issue seventh. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2015 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
10. State form of medicines. Issue eighth. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2016 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
11. State Form of Medicines. Issue ninth. - K .: State Enterprise "State Expert Center" Ministry of Health of Ukraine, 2017 [Electronic resource]. - Access mode: http://pharma-center.kiev.ua/view/formylar
12. State Register of Medicinal Products of Ukraine [Electronic resource]. - Mode of access: http://www.drlz.com.ua/
Published
2018-08-14
How to Cite
GadyakІ. V., & Hromovyk, B. P. (2018). Dynamics of prostate protectors assortment in the state formulary of medicines of 1-9 issues. Farmatsevtychnyi Zhurnal, (5-6), 7-15. https://doi.org/10.32352/0367-3057.5-6.17.01
Section
Management of pharmacy