Research of amino acid aerial parts Polygonum persicaria L.

  • I. A. Lukina Zaporizhzhia State Medical University
  • O. V. Mazulin Zaporizhzhia State Medical University
  • G. V. Mazulin Zaporizhzhia State Medical University
Keywords: amino acids, aerial parts, Polygonum persicaria L., medicinal herbs

Abstract

One of the most promising sources of amino acids are medicinal plants. Amino acids plant’s form a large group of organic compounds that have unique biological, pharmacological and toxicological properties. With a wide range of pharmacological actions and the ability to enhance the assimilation of other substances, amino acids have attracted large the attention of researchers as potential drugs. Since amino acids contribute significantly to the pharmacological activity of plants, it is necessary to take account of their content in the medicinal plants.

The aim of this study was to investigate the amino acid composition of the aerial part (inflorescences, leaves, herb) Polygonum persicaria L.

According to the method of Moore and Stein on high performance liquid chromatography conducted research to establish qualitative composition and quantitative content of free and protein-bound amino acids composition.

It was determined that, regardless of the morphological and anatomical parts of the plant these dominating amino acids: alanine, cysteine, arginine (nonessential), leucine, lysine, isoleucine (essential). Is defined the presence of 15 amino acids, 7 of which are essential. There was the greatest accumulation of amino acids in the inflorescence Polygonum persicaria L. (1,36 ± 0,0408%, 10,91 ± 0,3273%), differed slightly the concentration in the herb (1,09 ± 0,057%, 6,49 ± 0,1947% ) and in leaves (1,06 ± 0,0318%, 5,49 ± 0,1647%).

The research results will be used in the development of quality control methods on the investigational medicinal plant and will be counted for the prediction of the pharmacological effects of drugs derived from it.

References

1. Zhokhova EV, Goncharov M. Yu., Povydysh M. N., Derenchuk S. V. Pharmacognosy: Uch. for students of pharmaceutical colleges and technical schools. - M .: GEOTAR-Media, 2013. [Electronic resource] - Access mode: http://www.medcollegelib.ru/book/ ISBN9785970427248.html
2. Khortetskaya T.V., Mazulin OV, Smoylovskaya G.P. and others. Amino acid composition of plant material of Plantago media L. and Plantago altissima L. Flora of Ukraine // Zaporozhye honey. journ - 2012. - No. 3 (72). - P. 132-134.
3. Serbin A. G., Syra L. M., Slobodyanyuk T. O. Pharmaceutical Botany: Textbook / Ed. L. M. Syroi. - Vinnitsa: A New Book, 2007. 488 pp.
4. State Pharmacopoeia of the USSR: Vip. 2. General methods of analysis. Medicinal herbal raw material / Ministry of Health of the USSR. - 11th ed., Additional. - Moscow: Medicine, 1989. - Issue. 2: Medicinal herbal raw materials. - 400 s.
5. Oleshko G.I., Yarygina T.I., Zorina EV, Reshetnikova MD Development of a Unified Method for Quantitative Determination of the Amount of Free Amino Acids in Medicinal Vegetable Raw Materials and Extractive Medicines // Pharmatia. - 2011. - No. 3.- P. 14-17.
6. Simonian AV, Salamatov AA, Pokrovskaya Yu. S., Avanesyan A. A. Use of ninhydrin reaction for quantitative determination of α-amino acids in various objects: Method. recommendations - Volgograd, 2007. - 106 p.
Published
2018-08-14
How to Cite
Lukina, I. A., Mazulin, O. V., & Mazulin, G. V. (2018). Research of amino acid aerial parts Polygonum persicaria L. Farmatsevtychnyi Zhurnal, (2), 88-91. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/132
Section
Pharmacological, phytochemical research