Study of some pharmacotechnological, physico-chemical and pharmacognostic properties of common fennel (Foeniculum vulgare) fruit

Keywords: common fennel fruits, pharmacotechnological, physicochemical, pharmacognostic studies, technology

Abstract

The search for new drugs from medicinal plant raw materials is relevant for the practical medicine and pharmacy of our country. For their development, it is advisable to use plant sources that are widely spread in the territory of Ukraine, have a sufficient raw material base and low toxicity.

Information about the powerful multifaceted pharmacotherapeutic effect of Foeniculum vulgare, its sufficient raw material base, in Ukraine, and prompted us to study the fruits of this medicinal plant (determination of technological characteristics that would optimize the production process of obtaining medicines based on it).

The aim of the work is to study the technological indicators of medicinal plant raw materials – Foeniculum vulgare fruits, whole and crushed, for creating drug based on them, which would improve digestion processes, motor-evacuation function, and the functional state of the gastrointestinal tract.

During the research, bibliosemantic, pharmaco-therapeutic, physico-chemical, pharmacognostic and statistical research methods were used.

The objects of the research were model samples of Foeniculum vulgare fruits, extractive substances of whole and crushed fruits, degree of grinding, fractional composition, moisture content, coefficients of absorption and swelling in purified water and ethanol 95%, bulk volume and bulk density before and after medicinal plant raw materials shrinkage, total ash, fluidity, angle of natural slope. Considering several technological factors, the optimal ratio of raw materials:extractant (1:4) was studied and calculated to ensure the process of extracting common fennel fruits.

The technological properties of the medicinal plant raw material – common fennel fruit were experimentally investigated. The established pharmaco-technological indicators are qualitative parameters of the technology and allow to control and evaluate the technological parameters of medicinal plant raw materials of Foeniculum vulgare fruit, necessary for the process of manufacturing substances (extracts, infusions) and, based on them, medicinal preparations in various dosage forms.

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Published
2022-08-29
How to Cite
FylypіukO. М., & VyshnevskaL. І. (2022). Study of some pharmacotechnological, physico-chemical and pharmacognostic properties of common fennel (Foeniculum vulgare) fruit. Farmatsevtychnyi Zhurnal, (4), 84-91. https://doi.org/10.32352/0367-3057.4.22.09
Section
Pharmacological, phytochemical research