Red clever as perpetrating raw materials for creating medicines

  • O.O. Tsurkan -
  • T.V. Kovalchuk -
  • O.V. Burmaka -
Keywords: Trifolium pratense, aminoacid, identification, assay, HPLC

Abstract

17 aminoacids were identified and quantitated in Trifolium pratense Hovers. HPLC method of iden­tification and quantitation of aminoacids with derivatization by pheniltiocianate was developed.

Obtaine overall amount of aminoacids is about 3,96 %. Main compounds in analised samples were Aspartic acid and prolin with content about 1,48 % and 1,35 % respectivity.

Widely affordable and selective applications allows to identify and quantitate aminoacids in plant material without aminoacids analyzer.

References

Babaskin VS, Kiselevsky MV, Dobransky VS // Pharmacy.— 1992. - №3. - P.65.

Grodzinsky A.M. Medicinal plants. Encyclopedic reference book. - K .: The main edition of URE them. Bazhana, 1991. - P. 86.

Dukhanina IV // Chemical-pharmacist. magazine. - 2006. - №2. - P. 22 - 23.

Likhatsky PG, Firi LS // Medical Chemistry. - 2002. - №2. - P. 108 - 110.

Liu H.J. //.. Chromatogr. A. - 1994. - Vol. 670. ó P. 59ó 66.

Pappa-Louis A., Nikitas P., Agrafiotou P. et al. // Anal. Chim. Acta. - 2007. - Vol. 593. - P. 92 - 97.

Cohen SA. // Methods Mol. Biol. - 2000. - Vol. 159. - P. 39 - 47.

European Pharmacopoeia: 4th ed. - Strasbourg: European Department for the Quality of Medicines, 2004.-3416 p.

Published
2008-10-13
How to Cite
Tsurkan, O., Kovalchuk, T., & Burmaka, O. (2008). Red clever as perpetrating raw materials for creating medicines. Farmatsevtychnyi Zhurnal, (5), 114-118. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/1109
Section
Original Articles

Most read articles by the same author(s)

1 2 > >>