Antimicrobial and antifungal activity of 5-aryl-2-furamides

  • Yu.I. Horak -
  • M.D. Obushak -
  • V.S. Matiychuk -
  • R.V. Kutsyk -
  • L.M. Kurovets -
  • R.Z. Lytvyn -
Keywords: furan derivatives, arylation, 5-aryl-2-furancarboxylic acids, antimicrobial activity, antifungal activity

Abstract

5-Aryl-2-furancarboxylic acids were synthesized from arenediazonium chlorides and furan-2-carboxylic acid or methyl 2-furancarboxylate in die conditions of Meerwein reaction. 5-(R1-Phenyl)-N-R2- 2-furamides (R1 = 2-F, R2 = РhСH2; R1 = 2-F, R1 = 2-ОМеС6H4; R1 = 4-F, R2 = 3-CF3C6H4; R1 = 4-F, R1 = 4-FС6Н4) which showed antimicrobial and antifungal activity were obtained.

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Published
2009-02-17
How to Cite
Horak, Y., Obushak, M., Matiychuk, V., Kutsyk, R., Kurovets, L., & Lytvyn, R. (2009). Antimicrobial and antifungal activity of 5-aryl-2-furamides. Farmatsevtychnyi Zhurnal, (1), 100-105. Retrieved from https://pharmj.org.ua/index.php/journal/article/view/1048
Issue
No. 1 (2009): Farmatsevtychnyi zhurnal
Section
Original Articles
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