Synthesis and pharmakological activity salts on the basis of substitued of 2-oxoindolin-l-acetas and 9-aminoacridini
Abstract
With the purpose search optimization of compounds with antimicrobial activity on the basis salts of substituted of 9-aminoacridini and 2-oxoindolin-l-acetic acids the synthesis was carried out.
The structure of salts was confirmed by the data of the element analysis and IR-spectroscopy. Was fixed that 2-oxoindolin-l-acetas of 9-aminoacridin show bacteriostatic V and rise activity of sodium salt benzylpenicllin in subbacteriostatic concentration. Salt of 9-aminoacridin on classification by K.K. Sidorov concern to a class of mini-toxical substances.
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